Efficiency of platelet-rich plasma therapy in knee osteoarthritis does not depend on level of cartilage damage

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Effectiveness of Platelet-Rich Plasma Based on Gene Expression in Knee Osteoarthritis

Background: Intra-articular injection of Platelet-rich plasma (PRP) is an effective method for the treatment of patientswith knee osteoarthritis (OA). This study aimed to assess the effects of PRP injection on OA, based on gene expressionanalysis.Methods: A sample of 30 subjects with knee OA was asked to complete the Persian versions of the Intermittent andConstant Osteo...

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Intraarticular Injections of Platelet-rich Plasma (PRP)in the Management of Knee Osteoarthritis

  The clinical use of PRP therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. Another reason is the strong advertisement of PRP procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific eviden...

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intraarticular injections of platelet-rich plasma (prp)in the management of knee osteoarthritis

the clinical use of prp therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. another reason is the strong advertisement of prp procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific evidence...

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Effects of Platelet-Rich Plasma on Cartilage Grafts in Rabbits as an Animal Model

BACKGROUND Cartilage tissue has limited regenerative capacity and the management of cartilage defects has always been a challenging issue. Platelet-rich plasma (PRP) has been recently been used to improve healing of cartilage defects. In the present experiment, we aimed to investigate the effects of PRP on regeneration capacity as well as survival of the cartilage grafts in a rabbit model. M...

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Platelet-Rich Plasma Treatment in Symptomatic Patients With Knee Osteoarthritis

BACKGROUND With increasing frequency, platelet-rich plasma (PRP) preparations have been used to treat cartilage lesions to regenerate tissue homeostasis and retard the progression of knee osteoarthritis (OA). PURPOSE To determine the effectiveness of intra-articular PRP injections in active patients with knee OA and to evaluate clinical outcomes in patients with and without previous surgical ...

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ژورنال

عنوان ژورنال: Journal of Orthopaedic Surgery and Research

سال: 2019

ISSN: 1749-799X

DOI: 10.1186/s13018-019-1203-0